2022 Antibiotic Agricultural Compound Sales Analysis New Zealand

Total antibiotic sales quantities decreased by 12,389 kg (23%) to 41,033 kg in 2022. This was the fifth
year of consecutive decreases and was 42% below that reported in 2017. The main contributors to
the 2022 decrease were the polypeptides which decreased by 11,021 kg (88%) to 1,486 kg and the
macrolides which decreased by 837 kg (18%) to 3,770 kg.

Lower sales quantities were reported for eight of the sixteen classes evaluated with a combined
reduction of 12,875 kg compared to 2021. The total combined increase for the eight classes with
higher sales was 486 kg consisting mainly of the aminoglycosides (425 kg higher), the pleuromutilins
(18 kg higher), and the sulphonamides and trimethoprim class (18 kg higher). Excluding the
polypeptides from the 2022 sales total the quantity reported for the other 15 classes decreased by 3%
from 40,914 to 39,547 kg compared to the previous year.

Total quantities of critically important antibiotics decreased by 562 kg (8%) to 6,285 kg mainly due to
lower macrolides sales. There were also 8% decreases for the third- and fourth generation
cephalosporins from 131 to 120 kg and the fluoroquinolones which decreased by 14% from 35 to 30
kg in 2021.